CENTER RESOURCES

Special Services, Instruments or Devices

• Professional Nursing Services
• Professional Nutrition Services
• Professional Biostatistical and Informatics planning, data management, and analysis services
• Dexa/Body Composition
• Basic Specimen Sample Processing

Major Areas Of Investigation

Behavior Sciences

• Influencing Acceptability Among culturally Diverse Women Substudy
• Clinical Pharmacogenetics Antidepressants Responses in Hispanics
• Depression and Metabolic Syndrome in Hispanics
• Hispanics, built Environment and Metabolic Syndrome
• Optimizing Functional Magnetic Resonance Imaging: A Pilot Study of Food Craving
• Bio-Behavioral Basis & Management of Type 2 Diabetes and Depression (CALM-D)
• Bio-Behavioral Bases & Management of Metabolic Syndrome (CHARMS)
• Hispanic community Health Study
• Valproate Efficacy in Cocaine-Bipolar Comorbidity
• Optimizing Pharmacotherapy for Bipolar Alcoholics

Cardiology

• Cardiovascular Disease Risk Stratification Across Injury levels after CSI: Assessment of Need for Intervention and its Predictors
• EDEMA4: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Assess the Efficacy and Safety of DX-88 for the Treatment of Acute Attacks of Hereditary Angioedema
• Open-Label Patient Continuation of DX-88 for Acute Hereditary Angioedema Attacks

Endocrinology And Metabolism

• Islet Cell Transplantation Alone in Patients with Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression
• Islet Cell Transplantation Alone and CD34 Enriched Donor Bone Marrow Cell (DBMC) Infusion in Patients with Type 1 Diabetes Mellitus, Steroid-Free Regimen
• Islet Cell Transplantation in Patients with Type 1 Diabetes with Previous Kidney Transplantation
• Islet Cell Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression
• Diabetes Prevention Program Outcomes Study or DPPOS
• Type 1 Diabetes Trial net-The Natural History Study of the Development of Type 1 Diabetes
• Collaborative Islet Transplant Registry
• Steroid-Free and Long-Term Calcinerurin-Free Trial In Islet Cell Transplant
• Type 1 Diabetes Effects of Rituximab on the Progression of Type 1 Diabetes in New Onset Subjects
• Sugar, Obesity & Heart Disease Risk
• Effects of Human Leptin Replacement
• Soy Phytoestrogens as Replacement Estrogens – The SPARE Study
• Islet Transplantation in Type 1 Diabetes
• Strategies to Improve Long Term Islet Graft Survival
• Islet Transplantation Versus Intensive Insulin Therapy in Type 1 Diabetic Kidney Allograft Recipients

Infectious Disease

• Reducing Risks for Multicultural HIV+/- Women and Partners
• Adherence in HIV+ Women Recovering from Substance Abuse
• A Phase IV, Non-Randomized, Open-Label Trial Evaluating the Safety of 625 MG Formulation of Viracept when Administered to HIV Infected Women During Pregnancy

Immunology

• Human T-Cell Response to Sm Autoantigen: “The Immune System and Systemic Lupus Erythematosus”
• Immunity to Heterogeneous Nuclear Ribonucleoprotein (hnRNP) Autoantigen
• Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)
• Immunologic Mechanisms, biomarkers and Subsets in CFS
• Arthritis New Approaches to Pathogenesis & Treatment

Neurology

• A 24-Month Double Blind, Randomized, Multi-center, Placebo-Controlled, parallel group study comparing the efficacy and safety of 0.5 mg and 1.25 fingolimod (FTY720) administered orally once daily versus placebo in patients with relapsing remitting multiple sclerosis
• Mechanisms of Cytotoxic Cell Dysfunction in CFS

Oncology

• Quality of Life Intervention in Advanced Prostate Cancer
• Ethnicity & Determinations of Quality of Life following Prostate Cancer Treatment

Pediatrics

• Neurodevelopmental Outcome of In Utero Cocaine Exposure
• Brain MRI/MRSI in Children Exposed in Utero to Cocaine
• Improved Outcome Prediction in Galactosemic Newborns
• A Multicenter, Randomized, Open Label, Single, and Multiple Dose Study of the Pharmacokinetics and Pharmacodynamics of 2 Dose Levels of Pantoprazole Sodium Enteric-Coated Spheroid Suspension in Infants aged 1 through 11 Months with Presumed GERD
• A Multicenter, Randomized, Open Label, Single, and Multiple Dose Study of the Safety and Pharmocokinetics of 2 Dose Levels of Pantoprazole Sodium in Children Aged 1 through 11 years with Endoscopically Proven GERD
• A Multicenter, Open Label, Safety Study of 2 Doses of Pantropazole sodium Enteric Coated Spheroid Suspension in Infants Aged 1 through 11 Months with Presumed GERD
• A Multi-center, Open Label Pharmacokinetic, Pharmacodynamic, Clinical Symptoms, and Safety Study of Pantoprazole Delayed-Released Granules Administered as Suspension in Neonates and Preterm Infants with a Clinical Diagnosis of Gastroesophageal Reflux Disease
• Effects of Leptin Replacement in Children
• Type 2 Diabetes Risk Reduction of Minority Youth
• A Multicenter, Randomized, Open-Label, single and multiple-dose study of the pharmacokinetics and safety of two dose levels of Pantoprazole sodium tablets in Adolescents aged 12-16 years with a Clinical Diagnosis of GERD
• Effect of hepatitis C on Insulin Resistance in Children
• Sex and Gender Influences on Drug Involvement in Adolescence

OB/GYN

• Comparison of voided Vs Catheter Urine Culture for Diagnosis of UTI
• Cefpodoxime Vs Ciprofloxacin for Acute Cystitis
• A Phase III, double blind, randomized, controlled, multi-center study to evaluate the safety, immunogenicity, and efficacy of GalxoSmithKline Biologicals HPV-16/18 VLP/ASO4 vaccine administered intramuscularly according to the three dose schedule (0,1,6 month) in health adult female subjects aged 26 years and above
• A Multi-Center, double-blind, randomized, placebo controlled study of Amolimogene (zYc10) in the Treatment of high-grade cervical intraepithelial lesions (CIN2/3) of the Uterine Cervix
• A Phase IIIb, observer-blind, Randomized, multi-center study with two parallel groups to compare the immunogenicity of GlaxoSmithKline Biological’s HPV-16/18 L1/Aso4 vaccine versus Merck’s Gardasil types 6,11,16/18 recombinant Vaccine Merck&co, Inc, vaccine when administered intramuscularly according to a 3 dose schedule in health adult females 18-45 years of age.
• A Phase III, double blind, randomized, controlled, multi-center study to evaluate the efficacy of GalxoSmithKline Biologicals HPV-16/18 VLP/ASO4 vaccine compared to hepatitis A vaccine as control in prevention of persistent HPV-16 or HPV-38 cervical infection and cervical neoplasia, administered intramuscularly according to a 0,1,6 month schedule in health females 15-25 years of age